Glossary of Medical and Health Terms

Gastroenteritis

Gastroenteritis (also known as gastro, gastric flu, and stomach flu although unrelated to influenza) refers to inflammation of the gastrointestinal tract, involving both the stomach and the small intestine (see also gastritis and enteritis) and resulting in acute diarrhea. The inflammation is caused most often by infection with certain viruses, less often by bacteria or their toxins, parasites, or adverse reaction to something in the diet or medication. Worldwide, inadequate treatment of gastroenteritis kills 5 to 8 million people per year, and is a leading cause of death among infants and children under 5.

At least 50% of cases of gastroenteritis as foodborne illness are due to norovirus. Another 20% of cases, and the majority of severe cases in children, are due to rotavirus. The third significant viral agent is astrovirus.

Many different bacteria can cause gastroenteritis, including salmonella, shigella, staphylococcus, Campylobacter jejuni, clostridium, E. coli, yersinia, and others. Some sources of the infection are improperly prepared food, reheated meat dishes, seafood, dairy, and bakery products. Each organism causes slightly different symptoms but all result in diarrhea. Colitis, inflammation of the large intestine, may also be present.

Risk factors are consumption of improperly prepared foods or contaminated water and travel or residence in areas of poor sanitation. The incidence is 1 in 1,000 people.

Globally, gastroenteritis caused 4.6 million deaths in children in 1980 alone, most of these in the developing world, where the lack of adequate safe water and sewage treatment capacity contribute to the spread of infectious gastroenteritis. Harrison's Principles of Internal Medicine estimates the current total figure to be 2.4 to 2.9 million per year. The global death rate has now come down significantly to approximately 1.5 million deaths annually, largely due to global introduction of proper oral rehydration therapy.

The incidence in the developed countries is as high as 1-2.5 cases per child per year and a major cause of hospitalisation in this age group.

Age, living conditions, hygiene and cultural habits are important factors. Aetiological agents vary depending on the climate. Furthermore, most cases of gastroenteritis are seen during the winter in temperate climates and during summer in the tropics.

Associated ICD-10 codes: A09., J10.8, K52.

Source: http://en.wikipedia.org/wiki/Gastroenteritis

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